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587 For example, TF and TFR2 expression are upregulated in dopaminergic neurons in PD brains, and downregulated TFR expression has also been linked to the prevention of dopaminergic neuron degeneration

Therefore, compound 968 may provide new therapeutic strategies for the treatment of different types of cancers

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This modulation decreases the metabolism of the cardiovascular risk factor phenylalanine, ultimately reducing myocardial collagen deposition, lowering the cardiac weight index, slowing the progression of myocardial fiber thickening and necrosis, and preventing and ameliorating ISO-induced myocardial fibrosis ( 3.3 Antagonism targeting ion channel disorders Oxidative stress and inflammatory processes accelerate the development of atrial fibrosis, leading to increased collagen deposition and structural remodeling of the atria

68 (2), e12627