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Notably, CaMKK2 suppresses lipid peroxidation by increasing the activity of NRF2, a transcription factor that promotes the expression of anti-oxidative proteins [207, 208]

Hepatoprotective effect of N-acetylcysteine in trabectedin-induced liver toxicity in patients with advanced soft tissue sarcoma

Gabrawy, M

It is of interest to note that a class of tertiary -chloroacetamide-containing compounds such as RSL3 has previously been shown to induce a unique iron-dependent, oxidative, non-apoptotic cell death, selectively in KRAS-mutant cells, through covalently inhibiting glutathione peroxidase 4 (refs 34, 35, 36)

Contrary to this, one study has found a positive correlation between IL-37 and TNF- levels in the peritoneal fluid of patients with endometriosis