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Description

Neuroendocrinology 78 , 210216 (2003)

In SCI patients and rats, iron deposits in the motor cortex are significantly increased, triggering the accumulation of ROS, and eventually leading to ferroptosis in motor neurons

Some studies have shown that milk thistle can increase glutathione levels in the liver by more than 35%

In a study of hepatocellular carcinoma, it was found that overexpression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) can inhibit ferroptosis while promoting pyroptosis, whereas HMGCR knockdown produced the opposite results [299]