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The metabolic pathways that show significant changes in serum mainly include arginine and proline metabolism, taurine metabolism and taurine metabolism, and pyrimidine metabolism

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(1982) found that lung concentrations of arsenic in hamsters given weekly intratracheal instillations of As 2 O 3 , arsenic trisulfide or calcium arsenate differed by a factor of approximately 10-fold after 4 weeks