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BPH Surgery If you are experiencing severe symptoms or if other treatments have failed, surgery may be necessary

pmid:13554481CrossRefPubMedGoogle Scholar Doets EL, Int Veld PH, Szczecinska A, et al

The mechanisms underlying this age-related NAD+ depletion involve multiple factors, including increased consumption by DNA repair enzymes, reduced biosynthesis, and enhanced degradation by CD38 and other NAD+-consuming enzymes