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The primers used for qPCR amplifications were designed by the authors: HO-1 forward: 5-CTATCGTGCTCGCATGAAC-3

RA can also affect other body systems, including the skin, eyes, lungs, heart, and blood vessels1 Symptoms of Rheumatoid Arthritis The symptoms of rheumatoid arthritis can vary in severity and may come and go

doi: 10.1007/s11523-014-0305-1 47 StanislawRBurzynskiTJBurzynskiGSBrookmanS

The conflicting findings regarding M1 and M2 macrophage polarization suggest that the effects of NAC may be context-dependent, influenced by factors such as concentration, cell type, and specific microenvironmental conditions