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Through the causal relationship with these genes, NFKB is considered to be causally involved in the currently intractable diseases such as acquired immunodeficiency syndrome (AIDS), hematogenic cancer cell metastasis and rheumatoid arthritis (RA)

This is consistent with the lack of disulfide bonds in this protein

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When body weight was included as a covariate, the observed interactions between sex and condition persisted, indicating that sex effects were not driven by weight differences between sexes, in contrast to previous studies [37]