glutathione-s-transferase from the pathogenic fungus coccidioides immitis Fungal Phagocytosis in Absence of Oxidative Stress Response Proteins Coccidioides immitis Frontiers | Functional, Structural and

doi: 10.1021/acs.jpcc.3c03964 6 Al-ZahraniH

As it is overexpressed in the prostate tumor site but rapidly inactivated in systemic circulation due to binding to serum protease inhibitors like 2-macroglobulin (A2M) and 1-antichymotrypsin (ACT), PSA is considered an attractive target for small molecule prodrugs against prostate cancer (Lilja et al., 1991

Compared to exogenous nanocarriers that may introduce potential immunogenicity or toxicity issues, EGCG-metal nanocomplexes have a simple composition, primarily consisting of pharmacologically active ingredients, making them easier to control and more suitable for clinical translation

10.1038/nnano.2016.23 Nat

the pharmacokinetics and biodistribution of the GSH-targeted liposomes was visualized by analysis of the Rho-PE label in the liposomes after 12 daily intravenous bolus injections in hamsters, and compared to the un-targeted liposomes