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For example, in CRC and hepatocellular cancer, TFR can be targeted by miRNAs including miR-22, miR-31, miR-141, miR-145, miR-152, miR-182, miR-200a, miR-320, miR-758, and miR1946365, resulting in a disruption between TF and TFR and the following iron importing process (Zhang et al., 2020e)

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Bordoni M, Pansarasa O, Scarian E, Cristofani R, Leone R, Fantini V, et al

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Because GSH rapidly oxidizes outside cells, variables like collection time, processing delays, temperature, and anticoagulants significantly affect accurate measurement, particularly in the unstable reduced fraction of GSH [118]