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10 Diagnosis Diagnosis of CKD is typically performed using indirect methods which include measuring serum creatinine (sCr), blood urea nitrogen (BUN), urine specific gravity (USG), Symmetric Dimethylarginine (SDMA) and urine protein:creatinine (UPC) ratio

[76] pre-treated ADMSCs with SAG, as a specific signal agonist of the Shh signalling pathway, and found that the combination of SAG and TGF-3 significantly increased the gene and protein expression of NP-specific markers at the molecular level as well as the macromolecular level, and significantly changed the IVD height, water content, ECM content, and structure (Table 5)

VallejoCordoba, A

Nevertheless, the major caveat of using cationic liposomes following the induction of inflammation is elicited by the interferon- response in animal models (mice) [96]

W., & Lipshultz, L