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This approach is being evaluated in a number of different applications, where bioactive ingredients are being employed to scavenge free radicals, from using vitamin E in intravenous micelle formulations to scaffolds ( 5.2 Combined approaches for targeting the TME As previously mentioned, techniques are more commonly being used in combination to exploit the advantages of each individual technique and maximise the overall potential, as well as the ability to produce more than one therapeutic response

The off-period is not optional, it is part of the protocol that ensures long-term success