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Quercetin can regulate the PI3K/Akt/NF-B signaling pathway, promoting a transition from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype in microglia and macrophages, thereby effectively alleviating brain ischemia/reperfusion injury (85)

The Vd area is used to predict the amount of drug remaining in the body

Academic, San Diego, pp 271293 Magistretti PJ, Chatton JY (2005) Relationship between L-glutamate-regulated intracellular Na(+) dynamics and ATP hydrolysis in astrocytes