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Muscle definition: Striations become visible in previously smooth areas

In 2019, 64 Cu-NOTA-PSMA-PEG-Cy5.5-C dots tracer was used in another human phase 1 clinical trial for guiding the surgery of prostate cancer by PET and MRI imaging (NCT04167969).As a nanocomposite with high safety and excellent photothermal conversion efficiency, the silica-gold NPs have also been demonstrated to be potential therapeutic agents for plasmonic photothermal therapy of atherosclerosis (NCT01270139), 502,503 and photothermal ablation of tumors (NCT00848042, NCT04240639)