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FDA approves nivolumab plus ipilimumab combination for intermediate or poor-risk advanced renal cell carcinoma

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Baldassi D, Gabold B, Merkel OM

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Thus, CYP2E1-mediated metabolic activation of CCl 4 was shown to play a significant role in ROS production, and JNK-mediated PTMs in promoting mitochondrial dysfunction and acute liver injury