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The following sections will focus on the mechanistic roles of distinct epigenetic modifications in promoting drug resistance in AML (Figure 1)

[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Lima G.L., Paupitz J., Aikawa N.E., Takayama L., Bonfa E., Pereira R.M.R

Trichinella spiralis infection has been shown to induce inhibition of HCT-8 colorectal carcinoma in BALB/c mice as demonstrated by a decrease in size and weight of tumors [80]

Lithocholic acid, in particular, is cytotoxic if present at high concentrations, and physiologic mechanisms have developed to limit its toxicity, particularly in the bile ductules, as will be described in more detail later

& Sacco, S