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For Adults: If you've tried "everything" and still struggle each spring, your genetics may hold the answer

doi: 10.1074/jbc.C000588200

This inhibition leads to accumulation of AICART ribonucleotide, which inhibits adenosine deaminase, leading to an accumulation of adenosine triphosphate and adenosine in the extracellular space, stimulating adenosine receptors, leading to anti-inflammatory action