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Indeed, SLC1A5 is highly expressed in various solid cancers 73,76,77 , such as squamous lung cancer, in which it is responsible for approximately 50% of glutamine uptake 73

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doi: 10.1016/j.jfca.2017.01.001

In spite of 40 years of research the exact function of this protein is more complex than ever, but it has been found that these intracellular dimeric proteins, play a major role in the intracellular transport of endogenous compounds, metabolizes various electrophilic xenobiotics, ligand transport and thus protects cells against toxic effects [31], [87], [85]

UV irradiation induces DNA damage that can lead to nucleotide alterations and beneficial mutations (Lawrence et al., 1982)