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In CKD, reduced renal excretion leads to vanadate accumulation, which accelerates eryptosis through multiple metabolic disruptions (Vervloet et al., 2017)

20 and 21c)

Regulatory mechanisms of aging in aging-associated diseases The hallmarks of aging and aging-related diseases do not exist in isolation

Higuchi, R

In addition, the immune component of the barrier limits access of environmental antigens, while the biological component is maintained through colonization by commensal microbiota 70