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It was found that PC saturation matters cell division, migration, and signal transduction in the course of disease occurrence and stress response through influencing cell membrane fluidity (Additional file 1: Figs

10.1016/j.spinee.2012.12.002 33 KamataniT.HagizawaH.YarimitsuS.MoriokaM.KoyamatsuS.SugimotoM.et al (2022)

Illustrative peptide linkers include, but are not limited to GGGGS GGGGS GGGGS (SEQ ID NO:41), GGGGS GGGGS (SEQ ID NO:42), GGGGS (SEQ ID NO:43), GS GGGGS GGGGS GGS GGGGS (SEQ ID NO:44), S GGGGS (SEQ ID NO:45), GGGS (SEQ ID NO:46), VPGV (SEQ ID NO:47), VPGVG (SEQ ID NO:48), GVPGVG (SEQ ID NO:49), GVG VP GVG (SEQ ID NO:50), VP GVG VP GVG (SEQ ID NO:51), GGSSRSS (SEQ ID NO:52), and GGSSRSSSSGGGGSGGGG (SEQ ID NO:53), and the like

This is achieved through the stimulation of IGF-1 receptors, which signal cells about the availability of nutrients

Additionally, TKI-driven macrophage interactions can sustain the DTP cells phenotype through activation of the PROS1-AXL signaling axis (Zhang X