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Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, HIV infection, AIDS, certain endocrine disorders, iron deficiency, and subtotal gastrectomy)

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Liposomal glutathione bypasses digestive breakdown and allows for increased absorption and bioavailability. In a 2017 clinical trial, participants were given oral liposomal glutathione daily (500 mg or 1000 mg) for one month

F., Bovo, B., Nadai, C., Crosato, G., Carlot, M., Favaron, F., Giacomini, A., & Corich, V