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MiRNAs, first found in Caenorhabditis elegans by Lee in 1993 48 , can regulate multiple metabolic pathways in humans at the level of translation and transcription and play a key role in regulating tumor cell growth, migration, invasion, and inducing resistance to chemotherapy 49

However, some research has reported that glutamine supplements may decrease muscle soreness and improve recovery after intense exercise ( In fact, one study found that glutamine or glutamine plus carbohydrates can help reduce a blood marker of fatigue during two hours of running ( It has also been used to try to boost the immune function of athletes, but results vary ( Other research has found that it did not improve the recovery of carbohydrate stores (glycogen) in muscle when added to carbohydrates and certain amino acids ( In the end, there is no evidence that these supplements provide benefits for muscle gain or strength

doi: 10.1186/s12951022-013197 34 XuCLiuZXiaoJ

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Glutathione-mediated neuroprotection against methylmercury neurotoxicity in cortical culture is dependent on MRP1