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[4] Adequate B12 intake helps prevent megaloblastic anaemia, a condition characterised by the production of abnormally large, immature red blood cells that cannot effectively transport oxygen

Because of the loss of protective features and the damage they cause, chronic and neuropathic pain are viewed as disease states (Costigan et al., 2009)

The activation of TRPV1 has been linked to the calcium-dependent production and release of signaling molecules such as PLC, IP3, diacylglycerol (DAG), and PKC 21,22