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Javitt DC, Zukin SR, Heresco-Levy U, Umbricht D

Conversely, the extrinsic pathway of apoptosis is initiated by the binding of death ligands to death receptors, which activates downstream effector caspase-8, ultimately resulting in the activation of caspase-3, -6, and 7, thereby inducing direct cell death [94]

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Carnitine-acylcarnitine translocase deficiency is a rare autosomal recessive disorder of fatty acid beta-oxidation, with mutations in the SLC25A20 gene, associated with hypoglycaemia, hyperammonaemia, cardiomyopathy, liver dysfunction, muscle weakness, and encephalopathy

A computational model comparing intranasal delivery patterns between mice and humans has been developed for further pharmacokinetic studies [92]