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Mitochondrial inhibition prior to oxygen-withdrawal facilitates the occurrence of hypoxia-induced spreading depression in rat hippocampal slices

Janku F, De Groot JF, Javle MM, Penas-Prado M, Shroff RT, Luthra R, Banks K, Lanman RB, Conley AP, Broaddus R, Davies MA, Kopetz S , Yung WKA, Heymach J, Fu S, Shaw KR, Meric-Bernstam F

Whether the issue is likely benign or needs urgent attention, a telehealth visit can clarify the next steps and connect patients to in-person care when necessary

We mainly discussed the potential etiology and pathogenesis of MDD from the perspective of widely accepted theories, including the neurotransmitter and receptor hypothesis, HPA axis hypothesis, cytokine hypothesis, neuroplasticity hypothesis and systemic influence hypothesis

MasedaDZackularJPTrindadeBKirkLRoxasJLRogersLMet al