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In an open randomized trial that investigated the step-down approach, 60% of the patients who received a combination of immunosuppressants were in steroid-free remission compared with 35.9% in a conventional step-up treatment group at week 26 (Panaccione et al., 2011)

Sood N, Garg R

Prostaglandins are required for CREB activation and cellular proliferation during liver regeneration

Research in this area is ongoing, and it appears that exosome-based therapies could open doors to innovative treatment options that could offer more effective and safer alternatives for IS patients