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and (iv) scaffold functions that can support tumor modeling and sensing ( in vivo , highlighting the feasibility of therapeutic membranes rather than freely circulating carriers ( Against this backdrop, an electrospun nanofibers and gastric cancer lens is timely: it connects a rapidly innovating materials platform to clear unmet clinical needs in locoregional control, precision modeling for therapy selection, and biomarker-driven monitoring ( 2 Electrospinning principles and design space Electrospinning is well suited for gastric cancer research and locoregional therapy not merely because it produces nanofibers, but because it enables structural engineering