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First, using a parallel approach to our human study, we applied 1 H-MRS at ultra-high field (9.4T) to measure rats GSH content in the NuAc (Figure 2a-c) and divided animals as either High or Low-GSH (i.e., H-GSH and L-GSH) following a median split, following procedures in our human study (Figure 2d)

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Pyroptosis-driven immune dysregulation in COPD: molecular mechanisms and therapeutic implications

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