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Pregnant or breastfeeding individuals are generally not prescribed these medications due to safety concerns (FDA Wegovy safety warnings)

Straighten your leg and tighten your quadriceps

The decline of normal red blood cell production, caused by low levels of vitamin B12, can impair oxygen delivery

In these groups of patients with risk factors who are taking metformin, especially over the long term, the new MHRA guidance suggests we should consider checking vitamin B12 levels as part of annual review bloods this is a significant change to current typical practice