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Effects of oral sepiapterin on blood Phe concentration in a broad range of patients with phenylketonuria (APHENITY): results of an international, phase 3, randomised, double-blind, placebo-controlled trial

26 The results of our study also showed that oral administration of MK-677 for 6 weeks did not alter mRNA expressions of pituitary GH and hypothalamic GHRH and GHSR in the pituitary gland and hypothalamus or protein expression of GHSR in the hypothalamus

This is why treatments such as Botox and PDO thread lifts should always be handled by trained medical professionals, and peptide injections are no different

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