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Consequently, there is a progressive accumulation of the presynaptic protein -synuclein within intracellular fibres

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Here we replicated doses of LSD1 inhibitors we previously characterized to induce NK reactivity in pediatric brain tumors without exerting direct tumor cytotoxicity, as a model of co-administration, and measured viability using amine-reactive dyes and flow cytometry

The overproduction of ROS leads to different kinds of downstream impairments, including ferroptosis

6 Conclusion PD is a multifactorial neurodegenerative disorder, with neuroinflammation and ferroptosis playing critical roles in its pathogenesis