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Sometimes referred to as synthetic antibodies, aptamers are typically single-stranded DNA or RNA oligonucleotides with defined secondary motifs (e.g., loop, stem, or G-quadruplex) that confer them complex three-dimensional structures and the ability to recognize and bind targets with exceptional binding affinity and specificity to their target (102)

All microscopy experiments were done in triplicates

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Conversely, astrocytes also have beneficial roles during PD progression [21-22]

The proliferation program of SLECs, however, is supported by the shunting of glucose from bioenergetic to biosynthetic utilization