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Neck 37 (12), 17991807

163 Warburgs seminal work in the 1920s highlighted that cancer cells preferentially convert glycolytic pyruvate to lactate, even under aerobic conditions

The evolution of ketosis: potential impact on clinical conditions

FIGURE 10 C75 and baicalin can directly activate CPT1A (Tomita et al., 2005), and the ACC2 inhibitors TOFA and Soraphen ( However, overexpression of CPT1A may increase the FAO rate, promote cell metabolism, and accelerate cell apoptosis, which brings certain difficulties for the development of related drugs