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Moreover, oxidative stress causes an increase in O2 concentrations, which triggers the Haber-Weiss reaction and excessive production of the harmful hydroxyl radical (OH )

Symptoms include pain, burning, tingling, numbness, weakness, or a change in sensation to light touch, pain, or temperature, or the sense of body position

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Eussen SJ, de Groot LC, Clarke R, Schneede J, Ueland PM, Hoefnagels WH, et al

The current understanding of redox signaling and the intricate interplay between the various pathways involved in protection against oxidative and nitrosative stress is not complete