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A 2024 review of clinical studies in severe gram-negative infections reported clinical success rates of approximately 75%80% for fosfomycin combination therapy regimens, even in patients with MDR pathogens ( 5.3 Standardization gap The lack of standardization presents a pervasive challenge

Most studies have shown that the GM of MDD patients differs from that of controls at the phylum, class, order, family, and genus levels, but with a particular emphasis on differences at the phylum, family, and genus levels (Table 7)

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[Abstract] Drug Metab Dispos

The gut-meningeal immune axis: priming brain defense against the most likely invaders