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We know that long-duration proton pump inhibitor (PPI) use is often associated with lower magnesium levels and deficiency. Meacham says

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[DOI] [PMC free article] [PubMed] [Google Scholar] 186.Smith PM, Howitt MR, Panikov N, Michaud M, Gallini CA, Bohlooly-Y M, Glickman JN, Garrett WS

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