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Nevertheless, the medical community and the society continue to face a staggering burden: In 2021, an estimated 3.4 billion people, representing 43.1% of the global population, were living with a neurological condition, which accounted for 11.1 million deaths and 443 million DALYs, making neurological diseases the leading cause of disability worldwide

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( E ) Immunoblotting of kidney tissues for FtH, fibronectin, and -SMA protein expression in the obstructed kidneys of UUO mice that received iron dextran injections (UUO+Fe) compared with 2 other groups of mice

3.2.1 Root mean square deviation analysis of MAO-B inhibitors The RMSD plots of the protein and ligand were generated using 100-ns molecular dynamics simulations to demonstrate the temporal stability of the proteinligand complexes (Figure 6)

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