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This promotes the secretion of soluble chemotactic factors, such as CCL2, CCL22, CCL28, CXCL8, and CXCL12, which facilitate the recruitment of immunosuppressive cells, such as myeloid-derived suppressor cells (MDSCs), M2-like TAMs, and Tregs, into the tumor 2,5

These differences in molecular structure and metabolic entry points are summarized in Figure 1 , which schematically illustrates the distinct transporters, phosphorylation enzymes, and downstream metabolic pathways for glucose and fructose

Suleyman H, Buyukokuroglu ME, Koruk M (2001) The effects of Hippophae rhamnoides L

These findings underscore the crucial role of weight management in mitigating OS and its associated complications in PCOS patients

The large sample size, and randomised placebo-controlled design are significant methodological strengths in the current study