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This is because injections of TB4 into the hearts of mice (both injured and uninjured) basically kick-started repair processes and made the epicardium (the outermost layer of the heart) behave as it does in embryonic development

Compound 6 demonstrated no hepatotoxicity in single and/or repeat dosing 14-day dog safety studies, which reaffirmed the relevance of the bioactivation pathway as a causative factor in the hepatotoxicity with 1

Ellagic acid has also been shown to increase the activity of GSH-Px and SOD and to decrease the level of MDA in the striatum of PD mice (Wang et al., 2019)