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Although one would expect that this condition should slow tumor growth, cancer cells eventually develop processes allowing them not only to survive hypoxia, but also to become more aggressive

Likewise, several l-monobodies mimic pY peptide binding by also binding perpendicular across the central SH2 -sheet, which thereby enables access to the pY and +3 pockets that are located on opposite sides of the SH2 -sheet 12,14

All authors engaged in intellectual discussions, reviewed drafts, and approved the final version

Pts BMI ranged from 24.5 to 50 with mean of 35.3