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Moreover, GPX4 was revealed to be essential in hematopoietic cells including T cells, erythroid precursors, and myeloid cells [16,17,18]

Fibromyalgias complex nature, involving central sensitization, neuroinflammation, mitochondrial dysfunction, and altered pain processing, requires therapeutic strategies capable of healing at a foundational level

When ROS levels exceed a certain threshold, cells enter a state of senescence by halting their cell cycles and activating signaling pathways associated with aging, such as p16/Rb and p53/p21 [13]