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DN and associated complications Diabetic foot disease is significantly exacerbated in patients with DPN due to reduced sensation and impaired wound healing, elevating the risk of foot ulcers and infections and potentially leading to lower-limb amputations

Older Adults: If youre over 50 and new to saunas, consider a resting electrocardiogram (ECG) or stress test to ensure your heart can handle the higher temperatures

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Future emphasis should focus on improving the targeting specificity and effectiveness of gene therapy to minimize damage to healthy tissues, possibly achieved through enhancing delivery vehicles

Reported Side Effects Side effects appear minimal in most research subjects