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Pieces of the Puzzle The general features of hyperglycemia-induced tissue damage are shown schematically in Fig

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132,134 Moreover, neutrophil extracellular traps containing neutrophil elastase and DNAhistone complexes induce oxidative stress, cellular senescence, apoptosis, and BRB disruption, further contributing to vascular dysfunction

Table 1 Antidiabetic effects of peptides and protein hydrolysates identified from plants and their cognitive dysfunction