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Among the many substances that support this balance, glutathione plays an essential role

It has a relatively high global incidence (0.5 to 5%) and affects mainly women aged 20 to 50 years [1]

Topically, glutathione works on two levels: it neutralizes free radicals that trigger oxidative stress-induced pigmentation, and it shifts the skin's melanin production pathway from dark eumelanin toward lighter phaeomelanin

Int J Neuropsychopharmacol 14:106974

Its research profile makes it relevant for studies focused on GHRH receptor activity, GH pulse dynamics, pituitary response, IGF-1 signaling, metabolic regulation, and age-associated endocrine pathway models