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CYP metabolic activity of HLCs was analyzed following an adapted version of a previously described protocol (19)

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Monitoring: Hematocrit/hemoglobin: Watch for erythrocytosis

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Studies tracking radiolabeled peptide demonstrate metabolism primarily in plasma, with resulting amino acids entering normal metabolic pathways

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A treatment designed to delay the onset of symptoms would prolong and maintain the patients quality of life and significantly reduce health care costs

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These non-image forming ipRGCs also function to regulate pineal melatonin secretion, the sleep/wake cycle, and pupillary constriction (Fu et al., 2005

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