Considering Konzo is an Afro-centric disease that affects very isolated communities, global collaborations are necessary to utilize the most advanced scientific technologies to conduct high-throughput measures as presented in this work
We do not have the capacity as some commenters have suggested to undertake evaluation of DMHT devices
Dawson MA, Borthakur G , Huntly BJP, Karadimitris A, Alegre A, Chaidos A, Vogl DT, Pollyea DA, Davies FE, Morgan GJ, Glass JL, Kamdar M, Mateos MV, Tovar N, Yeh P, Delgado RG, Basheer F, Marando L, Gallipoli P, Wyce A, Krishnatry AS, Barbash O, Bakirtzi E, Ferron-Brady G, Karpinich NO, McCabe MT, Foley SW, Horner T, Dhar A, Kremer BE, Dickinson M
NaBPC157 In addition to a decrease of the otherwise raised blood pressure values, NaBPC157 also caused a marked attenuation or even abolition of the lesions and disturbances normally appearing in the various organs which were (after three weeks of an increased salt diet in the controls): very severe hyaline degeneration with prominent parenhymaous hemorrhages, degeneration of the arterial walls, vacuolisation of the cells in the heart, severe congestion (specifically medullar) in the adrenals, severe congestion, parenhymatous hemorrhage with hematuria in kidney and hemosiderosis and erythrocytophagia in the spleen
Nampt is critical for energy metabolism in retinal cells and its deficiency results in impairment of retinal homeostasis
