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Invest Ophthalmol vis Sci 38(13):27112720 Bursell SE, Clermont AC, Aiello LP, Aiello LM, Schlossman DK, Feener EP, Laffel L, King GL (1999) High-dose vitamin E supplementation normalizes retinal blood flow and creatinine clearance in patients with type 1 diabetes

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Positive values in the rank plot correspond to a positive association with response

Dosage: 0.25 to 0.5 mg daily Administration: Subcutaneous injection 1 to 2 inches from lateral epicondyle Frequency: Once daily, some split into twice daily Duration: 4 to 8 weeks for acute injuries, 8 to 12 weeks for chronic Timing: Evening injection may align with natural repair cycles during sleep Starting Conservative Beginning with lower doses and gradually increasing allows you to assess your response while minimizing any potential issues

The overall mean values for G6PD activity have to be optimized in individual laboratories to determine the cut-off points for moderate and severe G6PD deficiency