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Neovasculature is a promising target for cancer therapy

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The paracellular translocation of macromolecules up to 125 is carried out by a low-capacity leak pathway regulated by zonula occludens (ZO), occludins, and tricellulins (Odenwald and Turner 2017

In addition to butyrate, bacteriocins produced by gut bacteria can prevent CRC through their cytotoxic activities as it was demonstrated by clinical studies (274)

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