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Chemical Society Reviews

Monitor subjective energy and mood

ADVERSE REACTIONS: As with all protein drugs, a small number of patients may develop antibodies to the protein

These deposits are called tophi (See Figures: 7a and 7b: Tophi on Foot and Over Achilles' Tendon, Figure 8: Tophus on Elbow, Figure 9: Tophi on Hands, and Figure 10: Large Tophus of Finger ) and can be in numerous locations, but especially on the feet and elbows