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Further studies on the exact mechanisms by which these monomers affect ferroptosis and fibrosis are necessary to promote their clinical application

bioRxiv 34:114 Kros CJ, Steyger PS (2019) Aminoglycoside-and cisplatin-induced ototoxicity: mechanisms and otoprotective strategies

& Evans, J

ALKBH5-mediated m 6 A demethylation at two m 6 A residues in the 3'UTR of NFE2L2/NRF2 mRNAs, which are recognized by IGF2BP2, contributes to reduced mRNA stability and decreased NFE2L2/NRF2 expression in hypopharyngeal squamous cell carcinoma cells[171]