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CRediT authorship contribution statement Victoria E

Menogh Valentine

A 2023 meta-analysis of these trials concluded that probiotics (usually multi-strain combinations of Lactobacillus and Bifidobacterium ) led to a significant reduction in pro-inflammatory cytokines (like TNF- and IL-6) and a slight improvement in patients Expanded Disability Status Scale (EDSS) scores [201]

Challenges in microbial ecology: building predictive understanding of community function and dynamics

Indications: Treatment resistant hypertension Most often used as a supplemental drug that is added on to a daily treatment regimen for patients with hypertension that is not adequately controlled by a combination of lifestyle modification, thiazide diuretic, plus an ACE inhibitor or Angiotensin receptor blocker (Brook & Townsend, 2026)